Articles
Lorne Genome: True blue genomics
Across the Australian research landscape, small genome projects are pushing their heads above the ground. [ + ]
Lorne Genome: O Canada! Can we copy your example?
Canada was one of the first countries to hop on the genomics bandwagon after the human genome project was completed. Since 2001, the Canadian federal government has invested C$386 million into Genome Canada, an independently operated organisation with the role of coordinating and funding genomics and proteomics research across Canada. [ + ]
Lorne Cancer: Architecture and oncology
Susan Williamson discovers why the theme of tissue architecture is so prominent at this year's Lorne Cancer conference. [ + ]
Metabolomics - an important emerging science
As with any emerging science there is some controversy regarding nomenclature, but the newly formed Metabolomics Society seems to be adhering to a convention consistent with the other '-omic' sciences
[ + ]The human side of science: what is the archetypal researcher personality?
Are there some personalities that are better suited than others to a scientific career? To provide insight into this issue, The Science Advisory Board created the first-ever psychological profile of life science researchers
[ + ]Adjuvants: The problem with peptides and the DCtag advantage
Vaxine's Nikolai Petrovsky says peptide vaccines work well in highly inbred laboratory mice, but have consistently failed in clinical trials over the past two decades because humans are an outbred species. [ + ]
Adjuvants: the players
Several Australian companies are trialling new 'natural' and synthetic adjuvants that combine potent immuno-stimulatory activity with low toxicity. Australia's biggest biotech, Melbourne's CSL (ASX:CSL), is boosting its experimental vaccines with its Iscomatrix adjuvant system, a phospholipid-cholesterol formulation containing a purified saponin extract from the bark of the South American tree Quillaja saponaria. [ + ]
Adjuvant technology: a powerful brew
Shakespeare's witches, in 'Macbeth', were concocting mischief, not some nostrum to ward off plague, but some of the things that imbue today's vaccines with immunogenic fizz would not have been misplaced among the eldritch ingredients in their cauldron. [ + ]
Corporate governance can be biotech's Achilles' heel
Some Australian biotechs are getting creative with company structure. But analysts prefer their companies to play it straight. [ + ]
Better sampling, more analyses, bigger laboratories?
I'm a statistician. I don't know a mass spectrometer from a resonating horoscope. But it seems to me that many practitioners and researchers do not have an optimal balance between the various stages of their data collection
[ + ]Cell culture mapping system
In a recent project, electrophysiology researchers at Westmead Hospital in Sydney required a system to acquire and analyse signals measured using a micro-electrode array
[ + ]Planning for technology change
How effective LIMS software design can leverage evolving technologies to reduce risk and improve ROI. As the commercial LIMS marketplace evolves and matures, it continually faces the challenge of technology change
[ + ]Superacid - The world's strongest acid uncovered
Researchers at the University of California, Riverside have discovered the world's strongest acid. Remarkably it is also the gentlest acid
[ + ]Venture capital investment picks up the pace
Australian venture capitalists invested more than $1 million per week in Australian biotechnology in the past financial year, an increase on the previous year and a recovery to the historic level of two years ago. As in the past, a large portion of the investment was made by a small number of investors, and was received by a small number of investees. [ + ]
Crystallisation in silico - Figuring out the structures of biological macromolecules
When Francis Crick and James Watson deciphered the structure of DNA in 1953, x-ray crystallography became famous. X-ray crystallography has long since become the workhorse for structural studies of big biological molecules
[ + ]