Agilent xCELLigence RTCA eSight Multimode Real-Time Cell Analyser

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Monitoring cellular behaviour in real time is essential for understanding fundamental biological processes. The Agilent xCELLigence RTCA eSight Multimode Real-Time Cell Analyser offers a sophisticated method that combines label-free impedance-based analysis with live cell imaging capabilities. This combination is designed to enable precise and comprehensive cell analysis, encompassing cell health, function and morphology, thereby facilitating deep insights into cellular dynamics.

Central to the xCELLigence RTCA eSight Multimode Real-Time Cell Analyser is its capacity to continuously monitor cell behaviour while simultaneously capturing live cell images in multiple channels, including red, green and blue. This dual-mode functionality allows for the real-time observation of changes in cellular morphology, proliferation and adhesion strength, complementing traditional impedance-based measurements with visual data. Furthermore, the system’s versatile imaging capabilities, encompassing brightfield imaging and three fluorescence channels, accommodate diverse experimental requirements, thereby enabling seamless adaptation of experimental protocols.

The workflow is both streamlined and robust. Following cell seeding and schedule set-up through the user-friendly software interface, researchers can introduce experimental treatments directly onto the cells. Subsequently, the system autonomously acquires data using its proprietary biosensor technology while concurrently overlaying live cell images in real time. This synchronised approach facilitates comprehensive analysis of cellular responses, enhancing the interpretability of experimental outcomes.

By bridging impedance-based analysis with live cell imaging, the xCELLigence RTCA eSight Multimode Real-Time Cell Analyser offers researchers a multifaceted perspective on cellular dynamics, helping to advance their understanding of fundamental biological processes. With its sophisticated capabilities, the innovative platform gives researchers the chance to explore new frontiers in cell biology and drive scientific discovery forward.