CrestOptics CICERO widefield and spinning disk confocal system

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The latest spinning disk confocal microscope system from CrestOptics is the CICERO. The confocal microscope offers an all-in-one solution for widefield and confocal imaging and it allows users to simply switch between modes as their imaging requirements evolve. It can be integrated into any imaging set-up, transforming it into a user-friendly confocal system.

Widefield mode supports informative data collection from samples, such as cell monolayers and tissue sections, whereas the confocal mode allows higher-quality analysis of larger 3D structures, including organoids or whole organisms. Additionally, CICERO’s speed and light efficiency provide the capability for prolonged live imaging and the capture of fast cellular events, such as chromosome segregations and organelle trafficking.

CICERO makes high-end fluorescence imaging accessible to every laboratory, enabling a variety of applications. Life sciences, metrology and material sciences are among the disciplines relying increasingly on high-resolution 3D imaging. Both entry-level and challenging applications can be addressed by using LED (3 mm LLG) or multimode laser (SMA fibre) as illumination sources.

With its small footprint and weighing only 7.65 kg, the system delivers fast image acquisition speed (15K rpm) and sensitivity, easily enabling live cell imaging and large-scale 3D object imaging. Due to its large field of view (up to 22 mm FOV), the CICERO offers a minimal scanning process and can capture large samples in a single frame. With an excitation range of 390–750 nm and emission range of 430–850 nm, the device offers a wide wavelength coverage.

The product has been designed to fit upright and inverted microscope frames with a C-mount camera port to attach an imaging camera, providing maximum configuration flexibility. CICERO allows seamless integration with all major microscopy systems and offers an easy user experience. The disk is hosted in a sealed compartment, securing a dust-free environment.