Phenomenex Kinetex 5 µ core-shell column

Phenomenex has announced the addition of a 5 µ particle to its Kinetex core-shell product line. As the largest diameter particle in the family, Kinetex 5 µ core-shell columns are claimed to deliver better performance than 3 or 5 µ fully porous offerings, with no increase in backpressure.

The 5 µ media provides 90% higher average efficiencies compared to the same size fully porous columns and little to no method development is required to achieve improved performance on standard HPLC systems. Chromatographers can simply substitute these columns into reversed phase HPLC methods that use traditional fully porous columns.

The product delivers increased resolution and extends the scalability and portability of the product line. With the current range of available particle sizes, including 1.3, 1.7 and 2.6 µ, the same method can be transferred from UHPLC to HPLC to preparative LC with Kinetex core-shell technology. For users interested in small-scale preparative purifications, the product is available in Phenomenex’s Axia preparative hardware technology.

With fully porous particles, efficiency decreases as flow rate increases, resulting in loss of resolution and sensitivity and slowing the overall analysis time. Kinetex core-shell technology enables high resolution and sensitivity over an extended linear velocity without generating excessive backpressure, along with lower limits of detection and quantitation. By delivering improvements in speed and separation efficiency over traditional columns, Kinetex core-shell technology enables chromatographers to get good results on any LC or UHPLC platform along with potential reductions in solvent usage.