Phenomenex Kinetex EVO C18 columns

Phenomenex introduces 2.6 and 1.7 µm EVO C18 particle sizes, expanding the company’s Kinetex core-shell column family. The Kinetex EVO C18 columns offer good peak shape for bases, 100% aqueous stability and rugged pH stability from one to 12 by incorporating an organo-silica grafting process that utilises uniform, stabilising ethane cross-linking.

The product delivers the advantages of core-shell technology at low, neutral and high pH ranges, making it a good addition to any lab’s current reversed phase column portfolio. The smaller particle sizes extend the versatility and scalability of this media, which was introduced initially in 5 µm particles for HPLC and preparative HPLC work. The columns are suitable for any industry that relies on chromatography, including pharmaceutical drug discovery and development, clinical research, forensic toxicology, food safety and quality and environmental analysis.

The Kinetex core-shell line is claimed to deliver improved results, increased productivity and easy transferability compared to traditional HPLC/UHPLC media. The 2.6 µm columns offer performance comparable to sub-2 µm fully porous particles on both standard LC and UHPLC systems, but at lower backpressures. The 1.7 µm particle size is designed for use with UHPLC systems and is said to deliver around 20% greater efficiencies than fully porous media.

Both particle sizes are directly scalable to each other and to the existing 5 µm size, making method transfer between UHPLC, HPLC and preparative HPLC techniques straightforward. They allow researchers to achieve performance gains on their UHPLC and HPLC instruments while being able to take advantage of high, low and medium pH conditions to influence selectivity.