Phenomenex Luna Omega mixed-mode selectivities and particle sizes for columns

Phenomenex has introduced mixed-mode selectivities and particle sizes for UHPLC, HPLC and preparative work in the Luna column family.

The Luna Omega Polar C18 stationary phase delivers a wide elution window and combined high retention for polar and non-polar analytes. The phase is 100% aqueous-stable due to a polar-modified surface, providing flexibility in solvent and gradient system selection needed to achieve desired polar/non-polar analyte separation. It is offered in a high-performance 1.6 µm particle for UHPLC instruments as well as a low-pressure 5 µm particle for direct scalability to analytical HPLC or preparative work. The 5 µm particle is available in Phenomenex’s Axia-packed preparative columns.

The company is also introducing the 100% aqueous-stable Luna Omega PS C18, which delivers two distinct separation mechanisms at the same time. The particle surface of the PS C18 contains a positive charge that facilitates greater acidic compound retention through ionic interaction, while the C18 ligand delivers general reversed-phase retention. This mixed-mode selectivity is a valuable tool for greater separation between mixtures of compounds that have varying functional groups, such as peptides, pesticides or metabolite profiles. Additionally, the positive surface charge encourages good basic compound peak shape through the ionic repulsion of these compound species.

Luna Omega columns are suitable for a wide range of applications, including drug discovery and development, food contaminant analysis, environmental testing, toxicology and clinical research.