The micrOTOF-Q II provides high resolution and accurate mass LC/MS/MS performance in proteomics, biomarker profiling, metabolomics and other small molecule applications. It offers the on-the-fly Smartformula 3D method for the unambiguous sum formula determination of small molecules, even up to 1 kDa in mass.
The system is fully compatible with fast LC systems, offering specifications of mass resolution greater than 17,500 on up to 20 spectra/second.
Automated, routine molecular sum formula determination by accurate mass, combined with precision isotopic pattern matching, has proven improved specificity over accurate mass measurements. On this system, the SmartFormula 3D method combines the on-the-fly analysis of accurate mass and isotopic patterns of both MS and MS/MS spectra of the same compound, using a sophisticated relational algorithm.
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