Scientifica in vivo micromanipulators

Scientifica’s range of in vivo micromanipulators have the ability to be mounted onto most manufacturers’ stereotaxic frames and are suitable for microinjection, electrophysiology or viral injection experiments. The IVMs are available in one and three axes of movement.

The IVM Single is a single-axis in vivo micromanipulator with a long 70 mm of travel enabling deep positioning into in vivo samples and thick tissue slices. With an ultrastable design, the product has less than 1 µm drift over 2 h for long-term experiments. The LinLab software ‘creeper’ function means that the manipulator movement, speed and distance can be preset, allowing for smooth movement and minimising the risk of tissue damage. Electronic resolution is 20 nm and offers smooth movement with a minimum step size of 0.1 µm. The minimum speed is 1 µm/s and maximum speed is 4 mm/s. There are also unlimited memory positions via the LinLab software.

The IVM Triple has all the features of the IVM Single but has a travel distance of 70 mm in all three axes to reach deep within the sample.

The variety of brackets available mean that the IVM Single and IVM Triple can be attached to a range of probe holders, such as slimline probe holders, or rotated probe holders for the use of two IVM Single manipulators on the same sample. The option of a long back bracket facilitates 50 mm variation in the height that the manipulator can be set up. This, along with the 70 mm of travel, makes the mounting height easy to customise.

For users with limited space around their samples, the IVM Mini Triple and IVM Mini Single offer compact solutions. Both have the same ultrastable properties and smooth movement as the IVM Single and Triple. The IVM Mini Triple has three axes of motorised travel along with a rotational axis to allow for an adjustable approach angle.