Thermo Scientific FAIMS Pro Duo interface

Scientists in pharmaceutical, biopharmaceutical and clinical research laboratories can benefit from a differential ion mobility interface that is designed to increase productivity and data quality for qualitative and quantitative workflows.

The Thermo Scientific FAIMS Pro Duo interface supports biological mass spectrometry (MS) and extends differential ion mobility to a broad range of applications including proteomics, plasma profiling and targeted small-molecule quantitation. The interface enhances signal-to-noise ratios and expands sample coverage, which should allow users to explore complex samples with reduced matrix interference and increase the breadth and depth of their analysis.

Optimal performance across a wide range of chromatographic flow rates (100 nL/min to 1 mL/min) allows scientists to push the research boundaries in areas such as proteome coverage, quantitative analysis, glycoproteomics, single-cell proteomics and structural biology. By eliminating sample preparation steps and simplifying calibration, workflow efficiency is increased, meeting the needs of high-throughput laboratories.

The interface enhances orthogonal selectivity and suppresses matrix interference to increase workflow productivity, even for complex samples, allowing researchers to focus on answering scientific questions and driving discovery forward. It easily integrates with Thermo Fisher’s next-generation mass spectrometers, including the Thermo Scientific Orbitrap Tribrid mass spectrometers, Thermo Scientific Orbitrap Exploris mass spectrometers, Thermo Scientific TSQ Altis triple quadrupole mass spectrometer and Thermo Scientific TSQ Quantis triple quadrupole mass spectrometer.