Thermo Scientific Orbitrap Exploris 240 mass spectrometer

Thermo Fisher Scientific’s latest high-resolution mass spectrometer (MS) is designed to give proteomics, metabolomics, biopharmaceutical characterisation and small-molecule scientists the analytical performance required for research and high-throughput analysis. The system seeks to help drive discovery and identification with increased accuracy for confident scale-up, while operational simplicity and speed should streamline time to results.

The Thermo Scientific Orbitrap Exploris 240 mass spectrometer expands the Orbitrap Exploris platform and delivers sensitivity and resolving power across a wide dynamic range. With state-of-the-art system architecture and instrument control software, the system provides simple yet powerful data acquisition capabilities, addressing demanding analytical challenges for small- and large-molecule applications. The system offers positive/negative mode switching for comprehensive sample coverage, fast scan speeds and functionalities including Thermo Scientific AcquireX intelligent data acquisition workflow that enable greater automation.

The mass spectrometer is a flexible solution for high-performance biopharmaceutical characterisation and achieves good sensitivity for native MS analyses. With the Thermo Scientific Vanquish Duo UHPLC systems running in tandem mode, there is no more waiting during column equilibration; the mass spectrometer constantly acquires valuable data with all the available features of the Thermo Scientific Chromeleon Chromatography Data System (CDS) software.

The mass spectrometer is fully compatible with the Thermo Scientific FAIMS Pro interface to achieve enhanced identification of proteins and peptides. Improved quantitative performance for translational proteomics and high-throughput studies should enable researchers to accelerate the translation of discoveries into clinical applications.