Thermo Scientific Vanquish Online 2D-LC System

Thermo Scientific Vanquish Online 2D-Liquid Chromatography (LC) Systems offer a robust and flexible platform for scientists to characterise complex samples in depth with confidence.

The 2D-LC system leverages the performance and ease of use of Vanquish technology, while offering application flexibility and versatility for multidimensional liquid chromatography. Laboratories in fields such as pharmaceutical/biopharmaceutical R&D, food safety, environmental testing, omics and polymer analysis can take advantage of the flexibility of the system.

Integrating the online 2D-LC system with complementary LC assays is said to enable improved sample throughput while increasing confidence in results. The system presents an easy upgrade from existing single-channel standard Vanquish HPLC or UHPLC systems, without the need for dedicated equipment for each analysis type. Automated and complete workflows accelerate sample analysis time and maximise sample integrity.

The flexible, precise and easy-to-use interface means the system can characterise complex samples across a wide range of industries. Key applications include confident peak identification and purity analysis, even in difficult-to-separate analytes, and making legacy methods with UV detection and non-volatile buffer usage compatible with mass spectrometry (MS) detection.

Vanquish Dual split sampler technology enables users to switch between instruments without manual replumbing, utilising the 2D-LC system for confidence or Dual LC for productivity. For solvent modulation, the 2D-pump and T-piece can be used for improved resolution power in the second dimension and reduced resources (bench space and instrumentation).

The Vanquish Trap Heart-Cut and Simple Switch 2D-LC kit with valves and Viper Fingertight Fitting Systems offer an easy, tool-free fluidic connection that facilitates optimum chromatographic performance while enabling user-friendly installation and operation of the multidimensional liquid chromatography methods.