Waters Acquity CSH and XSelect UPLC and HPLC columns

Waters Acquity CSH and XSelect feature a wide range of selectivity choices and performance enabled by charged surface hybrid technology.

The Acquity UltraPerformance liquid chromatography (UPLC) and HPLC columns offer method development scientists additional selectivity choices and improved chromatographic performance for separations using acidic, low ionic strength mobile phases. The three new chemistries will be available in fully scalable UPLC, HPLC and preparative columns and particle sizes.

The Acquity CSH and XSelect HPLC columns feature Charged Surface Hybrid (CSH) technology - the CSH C18, CSH Fluoro-Phenyl and CSH Phenyl-Hexyl chemistries - for a wide range of selectivities. These UPLC and HPLC columns are claimed to offer sharper peak shapes for basic compounds, faster column re-equilibration after mobile-phase pH changes and improved batch-to-batch reproducibility for ionised compounds in acidic mobile phases.

The columns are available in 1.7 (UPLC), 3.5 and 5 micron (HPLC) particles and are suitable for HPLC and UPLC methods developed on the Waters Acquity UPLC H-Class System equipped with Fusion Method Development software from S-Matrix.

The CSH Technology-powered columns feature high-mass loading capacity for basic compounds and the ability to seamlessly scale separations between UPLC, analytical HPLC and preparative HPLC platforms. XSelect preparative HPLC columns utilise Optimum Bed Density (OBD) column hardware (up to 50 mm internal diameter) for long, predictable preparative column lifetimes.