Biomatters Geneious Pro version 5.0 sequence analysis software

Biomatters has released version 5.0 of Geneious Pro, its powerful but user-friendly sequence analysis software. This upgrade allows full bacterial genome assembly for data generated by Illumina, 454, SOLiD, Helicos and other sequencers to be done on a desktop computer and features many improvements to visualise, browse and analyse the large volumes of data created with next-generation sequencing.

Geneious Pro features a number of analysis tools for mutation detection, repeat finding and a split-screen viewer for opening multiple different views of the same sequence. For example, the ‘variation finder’ can detect all mutations in a novel bacterial strain by comparing it to an ancestral strain using the reference assembly method, to determine the underlying genetics of its observed phenotype. The split-screen view allows navigation of the genome by these annotations as well as support for in silico cloning and restriction analyses.

User testing with researchers around the world has focused on streamlining regular tasks and workflows to accelerate discoveries. Users can now move fluidly from primer design, to sequence assembly, to analysis within one platform. The Sequencher contig import option in Geneious Pro 5.0 allows users to recover prior analyses with little problem.

An unrestricted 14-day free trial of Geneious Pro is available from www.geneious.com.

Biomatters is currently beta-testing a software product called Geneious Server with a select group of institutions. Geneious Server will allow users to offload high-intensity computing associated with next-generation sequencing, phylogenetics and sequence analysis to servers and supercomputers, harnessing institutions’ existing computational resources for dramatic speed gains, as well as encouraging collaboration among teams of researchers.