CGH microarray software

Agilent DNA Analytics 4.0 software can be used for visually exploring, detecting and analysing patterns in microarray data. New in this release are: the ability to analyse more than 100 samples per experiment, a free genomic browser and copy number variation (CNV) analysis capability. These features join existing chromatin immunoprecipitation-on-chip (ChIP-on-chip), array-based comparative genomic hybridisation (aCGH), and gene expression analytics capabilities.

For large-scale experiments, Agilent DNA Analytics 4.0 can process more than 100 microarrays (244K), helping users easily compare data and visualise patterns. The package also includes a free genomic browser that enables researchers to easily share data and results with colleagues.

CNV research and discovery is a rapidly growing area of research where gains or losses of genomic DNA are increasingly being associated with certain cancers and developmental diseases. Using aCGH techniques, CNVs at multiple loci can be assessed simultaneously, allowing for their identification and characterisation. Agilent has added CNV capability to Agilent DNA Analytics to help users realise the full potential of Agilent microarrays.

Agilent has also updated its eArray online design tool for creating custom microarrays by expanding the CGH probe database from 8.4 to more than 24.5 million probes. This advance in microarray probe density and the addition of search capabilities specific to this content provide a more comprehensive coverage of genome, including CNVs.