Copy number analysis software

The Nexus Copy Number Professional version 3.0 software provides complete data integration, allowing thousands of arrays along with their clinical annotations from any array platform, such as Agilent, Affymetrix, Illumina, Roche Nimblegen and Empire Genomics, to be loaded and processed in a single project. Scientists can integrate gene expression and miRNA results obtained from any platform with their copy number project to further enable system level discoveries.

Visualisation of the data is augmented with advanced statistical methods enabling the researcher to identify areas of genomic ‘hotspots’ having a concordance of multiple events in a small area. Researchers can also identify biological functions affected by chromosomal aberations without specifying any a priori cut-offs.

Other features include many enhancements to the existing novel clustering scheme, including the ability to view clinical annotations on the dendrogram branches and factor enrichment, which allows the user to quickly identify clinical factors that are enriched in a particular cluster.