MBF Bioscience Neurolucida 360 for automatic neuron reconstruction

Neurolucida 360, from MBF Bioscience, is a neuroscience research tool for obtaining data about the size, shape and complexity of neurons from image stacks and big image data. It enables the user to quickly reconstruct dendrites, axons, somas, spines and synapses in a 3D environment.

The product works with 3D and 2D images acquired with confocal, two-photon and fluorescence microscopes or slide scanners. It excels at handling large images such as whole slide images or images of tissue cleared with CLARITY, Scale, iDISCO and more.

It can be difficult to follow a single dendrite in a neuron with significant branching, but the product enables users to rotate the neuron in 3D to get a better view of the dendrite and continue with the reconstruction. The tool is said to enable neuron reconstruction 15 times faster than other methods.