Molecular Health MH Guide 6.0 cancer genomic profiling software

Molecular Health has launched the latest version of its tertiary analysis solution for genomic profiling, MH Guide. The browser-based software is used by pathology laboratories and molecular tumour boards to automate annotation and clinical interpretation of increasingly complex genomic profiling in oncology, comparing next-generation sequencing data from molecular testing with information from one of the world’s largest and growing knowledge platforms (Dataome). Thus, the tool enables molecular pathologists and practitioners to keep pace with rapidly expanding medical knowledge.

With this latest update, the software’s comprehensive reports are further expanded with improved variant classification and more targeted matching of patient profiles to clinical trials. Furthermore, MH Guide 6.0 supports data from reference genome GRCh38/hg38, in addition to the still widely used GRCh37/hg19.

The latest version also allows bulk case exports for the purpose of documentation, downstream analyses or reporting to third parties. It includes refined variant pre-classification rules that leave less manual fine-tuning for users to do, and it integrates the processing of data from the two most commonly used human reference genomes.