Waters OneLab software with bioprocess walk-up solutions

Waters has announced its bioprocess walk-up solutions designed to simplify biologic sample prep and analysis. Enabled by updates to the company’s OneLab laboratory automation software and pre-developed analytical workflows, the combination allows bioprocess engineers to capture high-quality bioprocess and drug product data from any bioreactor with just a few clicks.

The updated OneLab software is at the heart of the bioprocess walk-up solutions. It incorporates pre-developed analytical workflows that simplify the user experience for routine product and process quality measurements of at-line samples from any bioreactor system.

Waters combines its BioAccord liquid chromatography-mass spectrometry (LC-MS) system and Andrew+ robot connected via new protocols in OneLab to create fully integrated and easy-to-use bioprocess walk-up solutions. This is designed to enable less experienced LC-MS users to acquire critical quality attribute (CQA) data for analysis of drug product and cell culture media.

Capturing data directly at the bioproduction laboratory can help bioprocess engineers improve process understanding, leading to more robust manufacturing processes and accelerated development timelines. By eliminating the need to send bioreactor samples to a central laboratory for analysis, the solutions are claimed to accelerate upstream bioprocess development by up to six weeks over traditional methods.

The integrated combination of software, automation and pre-developed LC-MS analytical workflows eliminates manual steps previously required for sample preparation, injection, data acquisition and data transfer. The impact is to reduce human errors and enable process improvements that can ultimately translate to lower downstream costs.