Meridian Bioscience VLP-RNA Extraction Controls

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Meridian introduces VLP-RNA Extraction Controls — a solution to monitor the extraction, reverse-transcription and amplification processes with a single, customisable control. Designed to integrate seamlessly with assay primers, the controls provide a straightforward and effective method to reduce false negative results in RT-qPCR assays. By applying VLP controls, users can achieve comprehensive performance validation across each stage of a molecular diagnostic (MDx) assay.

Meridian says that its VLP-RNA Extraction Controls consist of virus-like particle (VLP) shells, meticulously packaged with precise quantities of target RNA molecules. This biomimetic composition closely mimics a test sample, offering a full-process control that oversees the entire RT-qPCR assay workflow, from lysis and extraction to reverse transcription and amplification.

The innovative product is particularly beneficial for ensuring the accuracy of RT-qPCR assays, the company says. By closely monitoring each step of the process, VLP-RNA Extraction Controls help identify potential issues that could lead to false negatives, thereby enhancing the robustness and credibility of the results.

Designed to oversee the quality of the sample lysis step, the controls also maintain RNA stability in the presence of nucleases commonly found in biofluids. This means the integrity of the RNA is preserved throughout the assay, providing consistent data.

Meridian’s VLP-RNA Extraction Controls are crafted to deliver precise and dependable results for molecular in vitro diagnostics. The company’s knowledgeable tech support team is readily available to assist with any product or application-related inquiries.