Cellbox Ground and Flight live cell transport incubators

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Transportation of delicate living cells in biomedical research has long been a challenge. Conventional cryopreservation has limitations, particularly when dealing with fragile cells such as engineered iPSC-derived hepatocytes, often leading to cell damage and reduced viability. Cellbox Solutions offers a solution with its Cellbox Ground and Flight systems.

The Cellbox serves as a live cell transport incubator, specifically engineered for the secure transport of organoids, tissue patches, cellular 3D prints and other non-freezable cell types. It can be used when samples need to traverse across a campus, between institutes or even from one part of the globe to another.

The innovation lies in the portable nature of the Cellbox, eliminating the need for cryopreservation or cooling during shipment. A fully temperature- and CO₂-controlled environment means that samples are maintained in a suitable incubation state during transportation. The Ground version uses a pressurised CO₂ cylinder for transportation by car, train or foot, while the Flight version employs sublimation of dry ice, enabling it to comply with flight regulations and thus making it capable of transporting live cells by air.

This innovative transport solution was recently demonstrated in a collaboration between CellBox Solutions and time:matters, a biomedical company that was faced with the challenge of transporting engineered iPSC-derived hepatocytes from France to Canada. The active portable CO₂ incubator was found to maintain the cells at a precise temperature of 37°C and 5% CO₂ during the 16-hour transatlantic journey, resulting in a 91% cell viability rate upon arrival.

More information is available here and here.