Sophion Bioscience QPatch Compact semi-automated patch clamp solution

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QPatch Compact, by Sophion Bioscience, is a flexible, semi-automated patch clamp solution that is suitable for applications such as ion channel research and drug discovery. The product allows full control of gigaseal ion channel recordings in up to eight cells asynchronously in parallel.

The benchtop system is designed to offer an effortless patch clamp experience with minimum set-up and maintenance required. It is suitable for busy laboratories that require higher throughput than manual patch clamping can provide, as well as laboratories that need electrophysiology data but do not have trained patch clampers. Anyone can learn to patch-clamp using QPatch Compact in less than half an hour, the company claims.

With up to eight sites in parallel, the product provides sufficient throughput to rapidly obtain replicas and fuels data generation for the user’s next publication or medicinal chemistry program. In addition, it is a valuable tool for graduate and postgraduate teaching.

QPatch Compact features a Giga-Ω seal in physiological Ringer’s solution, so there is no need for seal enhancers or fluoride. It also offers water-based temperature control at each measurement site, manual liquid additions that provide full flexibility, on-the-run changing of protocols and Sophion Analyzer software designed for easy and automated data analysis.

The system’s QPlates are designed to enable consistent quality recordings time after time. Liquid exchange via microfluidic channels is fast and complete, while the glass surfaces prevent adherence of sticky compounds. With the inclusion of ready-to-use individual electrode pairs, there is no need to re-chloride electrodes again.