Wyatt Technology Mobius MP-PALS zeta potential analyser

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Wyatt Technology has developed an MP-PALS (massively parallel phase analysis light scattering) instrument for measurement of the electrophorectic mobility and determination of zeta potential (electrokinetic potential) of not only large particles, but also to measure protein samples including antibody formulations, bovine serum albumin and lysozyme, all down to 1 nm.

The device is said to be the first and only light-scattering instrument that makes reliable, reproducible and non-destructive electrophoretic mobility measurements of macromolecules as small as 1 nm under dilute solution conditions. The product was designed with the goal of measuring the mobility and hydrodynamic radius of precious protein samples without perturbing these fragile species. By overcoming the challenges presented by these delicate nanoparticles, the technological advancements embodied in the device offer new capabilities for traditional applications.