Merck’s Pellicon Capsule with Ultracel Membrane is a single-use tangential flow filtration capsule for bioprocessing of antibody-drug conjugates and monoclonal antibodies. The capsule is designed to reduce the risk of product cross-contamination, as well as exposure to toxic compounds during both processing and disassembly.
The self-contained design is suitable for the safe and easy removal of the entire single-use TFF flow path immediately after product recovery, optimising product changeover efficiency and saving time. The device requires no cleaning validation requirements, thereby reducing its footprint in the manufacturing environment. This should lead to increased plant productivity and process flexibility, with the added benefit of reduced contamination risks.
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