Successful antibody screening study

Therapeutic antibody supplier MorphoSys and technology company Biametrics will continue their collaboration in the area of high-throughput antibody screening following a successful feasibility study.

Biametrics performed the screening study using MorphoSys’ reagents and its own microarray-based b-screen device, recently launched for high-throughput biomolecular interaction screening/analysis, for the characterisation of Fab fragment antigen interactions. The study demonstrated the advantages of b-screen to speed up the overall antibody screening process using the microarray format.

The b-screen device enables the detection of biomolecules in a high-density array format on microscope slide disposables. No fluorescence labels are needed for readout, which leads to minimised sample pre-treatment and reagent consumption. The optical detection method makes it possible to reduce the complexity of the conventional label-free assays while enhancing the throughput and maintaining precision and reliability.

“We have identified b-screen as a promising technology in the field of epitope mapping and will now broaden our collaboration with Biametrics,” said Dr Markus Enzelberger, Senior VP, Head of Discovery Alliances & Technologies at MorphoSys.

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