Bio-Rad Laboratories Bio-Plex Pro Human Apolipoprotein Panel

Bio-Rad Laboratories has announced the launch of the Bio-Plex Pro Human Apolipoprotein Panel. The 10-plex panel allows researchers to rapidly detect and quantify key human apolipoproteins associated with cardiovascular disease, especially within the statin pathway, as well as the biomarker C-reactive protein.

Detecting changes in apolipoprotein levels can be difficult with traditional ELISA techniques because they require a large sample input. The Bio-Plex offers a multiplex solution with low sample requirements to accommodate the study of precious samples. In addition, the panel allows researchers to measure the level of C-reactive protein, a commonly used biomarker for a wide range of conditions, in the same assay as apolipoproteins, and can assess how these different analytes work in concert in the human body.

The product is a ready-to-use, 96-well kit containing premixed magnetic capture beads and detection antibodies, standards and buffers. It is claimed to offer the largest number of apolipoproteins on the market and includes four targets (Apo C1, Apo D, Apo J and Apo H) not found on other multiplex panels. It is compatible with platforms including the Bio-Plex 200, Bio-Plex 3D and Bio-Plex MAGPIX, as well as all Luminex platforms.

For scientists in both biopharma and academia exploring cholesterol metabolism and the statin pathway, the panel facilitates the robust, sensitive and high-throughput study of a variety of apolipoproteins across many disease areas, including cardiovascular and neurological disease, hypercholesterolemia, diabetes, obesity and sepsis.

The product is said to enable detection of more samples than any other available assay, allowing researchers to get more data out of each run. Featuring premixed, ready-to-use reagents, it saves time and simplifies workflow with clear instructions. It also includes Bio-Plex Manager and Bio-Plex Data Pro Software for efficient analysis and data management.