Cayman Chemical Lysosomal Staining Kit (Red Fluorescence)
Cayman Chemical’s Lysosomal Staining Kit (Red Fluorescence) is a convenient tool for imaging lysosomes in live cells. The kit utilises a red fluorescent dye that permeates the lysosomes based on pH gradient. Once protonated, the dye is unable to leave the lysosome, resulting in enhanced fluorescence.
The kit includes bafilomycin A1, which is an inhibitor of the vacuolar ATPase. Treatment with bafilomycin A1 results in decreased lysosomal fluorescence upon staining with the lysosomal staining reagent.
Lysosomes are intracellular organelles that contain enzymes used for the hydrolysis of waste materials and other cellular debris. The pH of the lysosome is ~4.5 to 4.8 and is optimal for these hydrolytic enzymes. The lysosomal pH gradient is maintained through vacuolar ATPases which pump protons into the lysosomes.
Phone: 02 9698 2022
Alamar Biosciences NULISAseq Mouse Panel 120 for protein biomarker analysis
The multiplex panel encompasses a wide selection of proteins essential for studying key...
Azure Biosystems Ao Microplate Reader
The 96-well Ao Microplate Reader from Azure Biosystems offers a multitude of features to help...
Navinci Naveni Plex isPLA multiplex solution
The isPLA multiplex solution is designed to simultaneously detect PD1/PD-L1 interactions...