Applied Biosystems has released genomic analysis tools that will help researchers in studies that associate genetic variation with specific diseases. These tools, known as the MeltDoctor High-Resolution Melt (HRM) Reagents, are for research use only and are part of a PCR-based workflow.
The MeltDoctor HRM Reagents facilitate high resolution melt, or HRM analysis, which is a powerful technique for the detection of mutations, polymorphisms and epigenetic differences in double-stranded DNA samples. These tools, including software, are part of an HRM analysis workflow optimised for Applied Biosystems real-time PCR systems that is simple to perform, requiring minimal quantities of both sample and reagent to capture a significantly greater amount of detail and information for variant types, without the complexity and expense of other methods.
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