IDT xGen Exome Research Panel v1.0

Integrated DNA Technologies (IDT) introduces its xGen Exome Research Panel v1.0 for insightful analysis of the human exome via next-generation sequencing.

A total of 429,826 probes span 39 Mb of the human genome, providing deep and uniform coverage of 19,396 genes. This leads scientists directly to relevant mutations, aiding advances in clinical and companion diagnostics research. By using the research panel with xGen Lockdown Reagents and the optimised protocol, scientists can obtain reproducible exome data in a single day, minimising the need for added downstream analysis.

Each probe within the research panel is individually synthesised and undergoes a rigorous manufacturing and quality assessment process in accordance with GMP standards. Missing or truncated probes are identified by mass spectrometry and OD measurements and are eliminated before pooling. This approach selects for full-length probes, enabling uniform coverage. Batch-to-batch variation is also minimised, ensuring consistent results between panels. The product provides scientists with the data they need to thoroughly interrogate their genomic sample of interest.

The research panel is the latest addition to IDT’s expanding genomics portfolio. The versatile technology is compatible with common sequencing platforms, including Illumina and Ion Torrent sequencers.