Lonza human and animal hepatocytes for ADME-Tox testing

Lonza now offers a comprehensive portfolio of human and animal hepatocytes for ADME-Tox testing. The range includes both fresh and cryopreserved human and animal hepatocytes, supporting researchers with a variety of in vitro applications, including studies into drug metabolism and toxicity, drug-transporter activity and drug-drug interactions.

The hepatocyte portfolio also features hepatic non-parenchymal cells, such as stellate and Kupffer cells, which can improve the translatability of in vitro toxicity testing and pharmacokinetics research to clinical trials. The hepatocytes are prequalified for a variety of different applications, which helps to reduce time spent evaluating cells for specific experiments within the laboratory.

The range also includes supporting ADME-Tox products such as specialised hepatocyte media and cell culture systems, helping to optimise hepatocyte culture performance for in-vitro drug screening or for research into drug-induced liver injury and other important liver diseases.