Sphingomyelin is found in mammalian cell membranes, especially in the membranes of the myelin sheath. It is the most abundant sphingolipid in mammals and is found mostly in the exoplasmic leaflet of the membrane, although there is also evidence of a sphingomyelin pool in the inner leaflet of the membrane.
Sphingomyelin is an important amphiphilic component when plasma lipoprotein pools expand in response to large lipid loads or metabolic abnormalities. It is also involved in signal transduction and apoptosis. An improper ratio of sphingomyelin to ceramide has been shown to be a factor in Niemann-Pick disease and neonatal respiratory distress syndrome.
Matreya’s Sphingomyelins are distributed in Australia and New Zealand by Sapphire Bioscience.
Phone: 02 9698 2022
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