Meridian Bioscience Specimen-specific, inhibitor-tolerant master mixes

Scientists can skip DNA/RNA extraction with Meridian’s inhibitor-tolerant, specimen-specific master mixes, designed to enable direct detection without compromising performance.

The master mixes have been optimised for highly sensitive amplification on crude samples such as blood, serum, saliva, urine and stool. The ability of the mixes to tolerate the high level of PCR inhibitors present in these different sample types allows the development of simple, fast multiplex qPCR assays that require minimal sample processing and fast turnaround times (TAT). This makes them suitable for liquid biopsy and point of care testing (POCT), where speed, sensitivity and reproducibility are essential.

The latest products include Genotyping Blood DNA qPCR Mix (ODX001), Blood DNA qPCR Mix (ODX002), Blood RNA/DNA qPCR Mix (ODX003), Urine DNA qPCR Mix (ODX004) and Stool DNA qPCR Mix (ODX005). Meridian Bioscience also provides options for molecular diagnostics assays, available as wet mixes or dried by lyophilisation or air-drying; there are several advantages to this, including room temperature shipping and storage, extended shelf-life and increased flexibility in the sample volume.