nanoTherics magnefect nano II Duo and magnefect LT Duo transfection devices

The nanoTherics magnefect-nano II DUO and the magnefect-LT DUO transfection systems enable up to 192 transfection experiments to be performed in parallel. The compact devices offer gene transfection with improved efficiencies and cell viabilities, even with a range of difficult cell types including neuronal and primary cells.

They use technology which applies oscillating magnet arrays to promote magnetic nanoparticle/DNA uptake into cells to improve non-viral gene transfection, while maintaining high cell viability.

They are said to be simple to use, providing improved transfection efficiency and effectiveness over the best currently available cationic lipids at short transfection times (<30 min). They allow retransfection as well as adherent state transfection for user flexibility.

The magnefect nano II Duo provides full flexibility with interchangeable 2 x 6-, 24- and 96-well magnet array formats and variable oscillating frequency capability to enable researchers to optimise protocols to maximise transfections specifically for the cell types they are using. The magnefect LT Duo is a lower-cost system with fixed oscillating frequency and fixed 2 x 6-well or 2 x 24-well or 2 x 96-well magnet array formats.

The oscillating magnetic field technology from nanoTherics is said to improve delivery of important molecules, such as DNA, into living cells. The medium- to long-term opportunity for this approach relates to more effective non-viral gene therapy, an area demanding safer technology to treat genetic diseases and disorders including cancers, Parkinson’s disease, multiple sclerosis and cystic fibrosis.