Protein characterisation

Wyatt Technology has launched the DynaPro range.

Acquired during Wyatt's acquisition of Proterion/Protein Solutions the dynamic light scattering (DLS) system is for protein crystallisation.

The products are for batch dynamic light scattering and are its primary offering in the field of high throughput screening.

The DynaPro range allows users tools for characterising unfractionated samples via DLS. The products particularly appeal to users doing rapid characterisation of size and polydispersity.

The range incorporates the automated DynaPro Titan Plate Reader, making the technology available for the rapid screening of unfractionated samples for applications such as crystallography and aggregation studies.

The range is claimed to offer the highest sensitivity and lowest sample volumes for protein crystallisation by DLS. It comes with a range of features including a control module with the ability to collect and analyse data and a read module, which comes as either a temperature-controlled scintillation vial reader for single measurements, or a fully automated plate reader with the capability to make measurements on 96 or 384 well plates.

Other features include a standalone self-desiccating temperature chamber for low temperature conditions and the ability to integrate with Wyatt's online accessories. The system comes with software which will be integrated into the 21 CFR 11-compliant Astra platform. The software complements multi-angle light scattering detectors to make absolute molecular weight determinations a desirable alternative to traditional liquid chromatography methods.