Seegene Allplex HPV HR Detection 3 Ct PCR assay

Seegene has announced its Allplex HPV HR Detection PCR assay applying ‘3 Ct’ technology.

In a polymerase chain reaction (PCR), the cycle threshold (Ct) value is used to quantify the concentration of a viral DNA sequence (the target). Due to technological limitations, the conventional real-time PCR technique finds the Ct value of one target in one channel. Seegene’s 3 Ct technology can provide the Ct value of three targets in one channel without compromising sensitivity and specificity, combining 19 different patented technologies including DPO, TOCE and MuDT. Using five channels in a single tube, the company can provide quantitative data for a total of 15 targets.

Seegene’s first 3 Ct technology applied product, Allplex HPV HR Detection, is designed to detect 14 high-risk human papillomavirus (HPV) types that can cause cervical cancer. It also provides the individual Ct value of each of the types, allowing quantitative analysis regarding infection level. In comparison, HPV products from other industry players provide individual Ct values for two high-risk types, HPV 16 and 18. The product will be compatible with Seegene’s fully automated AIOS (all-in-one system).

The company plans to apply 3 Ct technology to its entire product line-up, including respiratory virus (RV), sexually transmitted infection (STI), gastrointestinal infection (GI) and urinary tract infection (UTI) assays. By detecting the causative pathogen, level of infection and potential of co-infection, it will help determine the priority of treatment and enhance patient management. The technology should also increase testing capacity.