Biomedical research centre at USQ

The University of Southern Queensland's efforts in biomedical research are set to enhance the University's national and international standing, according to Dr Mike Kotiw, director of the centre for biomedical research.

The centre engages in biomedical research that is focussed on understanding and controlling processes associated with a number of human diseases. "Our research uses molecular and conventional technologies to provide improved diagnostic and therapeutic solutions for the management of both infectious and non-infectious syndromes," Dr Kotiw said.

"We have some very gifted scientists performing important research in the centre. For example, our Dean of Sciences, Professor Stuart Hazell is a world recognised expert on the pathogenesis and control of the bacterium helicobacter pylori."

Dr Kotiw said that part of the research into the helicobacter pylori was directed to developing a recombinant vaccine against the bacterium which could be used reduce the risk of colonisation in children or possibly have a therapeutic value in infected patients.

Of particular interest to Dr Kotiw's research is a program investigating the pathophysiology and control of endotoxaemia-associated endotoxic shock syndrome. This syndrome is induced when certain intestinal bacteria enter and grow in the blood stream as a result of traumatic events such as car accidents or major surgical procedures.

"Our research is focussed on two paths, the first is to be able to determine, as quickly as possible, if a patient is indeed suffering from endotoxic shock and not some unassociated syndrome. In collaboration with some other researchers we hope to be able to identify drugs which may protect the deterioration of the gut wall during such ischaemic events and consequently prevent the hyperinflammatory cascades which ensue from the translocation of bacteria through the gut wall."