Genome of potential bioremediation agent deciphered

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Thursday, 10 October, 2002

Scientists at The Institute for Genomic Research (TIGR) in the US and collaborators elsewhere have deciphered the genome of a metal ion-reducing bacterium, Shewanella oneidensis, that has great potential as a bioremediation agent to remove toxic metals from the environment.

The genome sequence sheds new light on the biochemical pathways by which the bacterium reduces and precipitates chromium, uranium and other toxic metals. The research offers a starting point for defining the organism's electron transport systems and metal-ion reducing capabilities.

In the course of the sequencing project, scientists also discovered a new bacterial phage (a virus that infects bacteria) that may provide a wedge for possible genetic manipulation of Shewanella to target it for specific bioremediation projects.

"This is a very important model organism for bioremediation research because of its unusual capacities to remove environmental pollutants under diverse conditions," said John F. Heidelberg, a TIGR assistant investigator. "Shewanella is the first microbe we have sequenced that can function for metal bioremediation and also survive in both aerobic and oxygen-free environments."

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