Capillary Electrophoresis Software

Beckman Coulter has 32 Karat software for its P/ACE MDQ Capillary Electrophoresis (CE) systems. Designed for the biotechnology and pharmaceutical industry, this platform will help users comply with FDA regulations such as 21 CFR part 11, concerning electronic data records and signatures. 32 Karat for CE also provides powerful capabilities for analyte identification.

The CE software is an extension of the 32 Karat platform developed entirely in 32-bit code. It utilises the functionality of Windows NT and preserves the integrity of data with features such as user-specific log-in, independent audit trails and results sign-off.

In addition to extending the 32 Karat platform to CE, this software adds analysis dimensions that increase the accuracy of compound identification. New peak identification algorithms allow the P/ACE MDQ to combine an analyte's mobility with spectral information for accurate identification against a large database of drugs.

These capabilities extend the applicability of CE into routine drug screening applications. Mobility-based analysis improves the robustness of assays, making it easier to put CE to work in a regulated environment.

The P/ACE MDQ is delivered as application-specific systems for the analysis of chiral pharmaceuticals, basic drugs, glycoproteins, carbohydrates and nucleic acids. These systems include the software, hardware and chemistry required to perform the analytical task.