Using CRISPR and transposons for CAR T cell production
21 December, 2021 by Marwan Alsarraj*, Biopharma Segment Manager, Digital Biology GroupCAR T cells are most often manufactured using viruses, but new research is exploring the benefits of using alternative gene editing systems for this purpose.
Found: a genetic link to non-alcoholic steatohepatitis
10 December, 2021Researchers found that albino mice with a point mutation in the tyrosinase gene are more susceptible to NASH than mice carrying the non-mutated gene.
Gene editing used to create single-sex litters of mice
09 December, 2021UK scientists have used gene editing technology to create female-only and male-only mice litters with 100% efficiency.
CRISPR gene editing can favour cells with cancer-linked mutations
22 November, 2021The findings point to a need for caution in the use of CRISPR-based gene therapies.
Genetic risk factors identified for spine osteoarthritis
17 November, 2021HKU researchers helped identify that the SOX5 gene, which is known to be essential for the development of the intervertebral discs, is implicated in spine OA.
So-called 'dust specks' are actually genome building blocks
09 November, 2021Tiny 'microchromosomes' in birds and reptiles are linked to a spineless, fish-like ancestor that lived 684 million years ago.
Mapping the epigenetic signatures of pain
20 October, 2021Scientists carried out a complete epigenomic study to define specific biomarkers for each type of pain, in order to be able to categorise the various types of pain quickly.
A single gene helps regulate the sleep–wake cycle
12 October, 2021Using the genetic model organism Drosophila melanogaster, researchers discovered that the Nf1 gene is essential for the regulation of the sleep–wake cycle.
Genetic trigger for type 1 diabetes may be in the lungs
17 September, 2021New research supports a theory that respiratory viral infections can trigger the onset of type 1 diabetes.
New regulatory regions uncovered on the human genome
07 September, 2021By analysing genomic data from more than 30,000 people, researchers revealed thousands of new regulatory regions that control disease-linked genes.
Identifying genetic causes of childhood epilepsy
02 September, 2021Genetic testing is crucial in epilepsy patients in order for them to receive appropriate counselling and treatment.
NSW Govt support to advance mRNA research
25 August, 2021The NSW Government has announced support for the state's leading universities, research institutions and hospitals to further advance mRNA research.
Exploring the mouse microbiome
20 August, 2021Researchers in the Adams Labs at The Jackson Laboratory for Genomic Medicine are focused on the creation of different assays and analyses to help study the microbiome.
Gene variant linked to autism spectrum disorder
09 August, 2021Researchers have shown that a deficit in histone methylation could lead to the development of autism spectrum disorder (ASD).
LSBio cDNA clones and expression-ready ORF clones
03 August, 2021LSBio offers a broad selection of over 13,000 cDNAs, each available in either a cloning vector or one of 14 different ready-to-use expression vectors.
