Shimadzu Ultra Fast Mass Spectrometry (UFMS) instruments

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Until now, when quadrupole mass spectrometers were run at fast scan rates, sensitivity dropped off dramatically, particularly at higher masses. In addition, mass shifts are seen at these higher scan rates. Shimadzu’s single and triple quadrupole mass spectrometers incorporate technology which is claimed to ensure that both sensitivity and mass spectral integrity are maintained at high scan rates, delivering high-quality data which is uncompromised at high speed and fast cycle times.

With triple quadrupole mass spectrometers, the usual rate determining step for overall acquisition speed is the collision cell, q2. The company’s UF-Sweeper technology allows 555 (LCMSMS) and 600 (GCMSMS) transitions/sec while maintaining almost zero crosstalk. This, combined with very fast scanning, allows dramatically shortened run times when used with the company’s Fast-GC and UHPLC instruments. This facilitates improved productivity and the ability to analyse multiple overlapped peaks and/or samples in challenging matrices, whilst maintaining high-quality qualitative and quantitative data.

The company has introduced its three latest triple quadrupole mass spectrometers. The LCMS-8040 and LCMS-8080 expand the analytical range of the LC-MS/MS line-up, while the GCMS-TQ8030 adds to the GC-MS history. The company’s LCMSMS instruments deliver steady ± polarity switching within 15 ms, allowing for the analysis of positive and negatively charged species within a single sample run.