Research & development > Clinical diagnostics

Mitochondrial dysfunction precedes memory loss in Alzheimer’s disease

02 March, 2012 by Brian Kilen

Mitochondria - subunits inside cells that produce energy - have long been thought to play a role in Alzheimer’s disease. Now, Mayo Clinic researchers using genetic mouse models have discovered that mitochondria in the brain are dysfunctional early in the disease.


Allied announces Coridon to develop HPV therapeutic vaccine

29 February, 2012

The board of Allied Healthcare Group has announced that its investment company Coridon has embarked on the development of a next-generation therapeutic Human Papillomavirus (HPV) vaccine. The program will be based on preliminary work by Coridon founder Professor Ian Frazer’s team and follows on from Professor Frazer’s work that resulted in two successful cervical cancer preventative vaccines - Gardasil and Cervarix.


Improved UOW anti-cancer formulation patented in Europe

21 February, 2012

A novel formulation for the treatment of metastatic colorectal cancer, developed by University of Wollongong researchers, has been granted patent rights by the European Patent Office. The formulation, called Fluorodex, was developed to address key adverse events associated with current treatment regimens that are used to combat metastatic colorectal cancer.


Method for determination of crotamiton

24 January, 2012

Thermo Fisher Scientific has developed an efficient quality control method for the determination of the cis and trans isomers that comprise crotamiton, used in the treatment of scabies and skin pruritus. The method is more efficient than the official protocols of the British Pharmacopoeia (BP) and Pharmacopeia of the People’s Republic of China (PPRC).


Research identifies mutations underlying human hereditary hearing loss

16 January, 2012

Hereditary hearing loss is the most common sensory disorder in humans. A German research team led by Ingo Kurth from the Institute of Human Genetics at the University Hospital Jena, Germany, used a number of different methods, including Roche’s NimbleGen Custom Sequence Capture 385K array, to identify the gene mutated in the disease locus of the X-chromosome of a Spanish family with hereditary hearing loss.


Educating stem cells reverses Type 1 diabetes

13 January, 2012

Type 1 diabetes is caused by the body’s own immune system attacking its pancreatic islet beta cells and requires daily injections of insulin to regulate the patient’s blood glucose levels. A new method described in BioMed Central’s open access journal BMC Medicine uses stem cells from cord blood to re-educate a diabetic’s own T cells and consequently restart pancreatic function reducing the need for insulin.


JW - bold in para 1 - sense? DB Award for Gamma Knife brain treatment

02 November, 2011

A major award to research a treatment for a dangerous and silent brain abnormality has been received.


Possible link between bacterium and colon cancer

21 October, 2011

Scientists at Dana-Farber Cancer Institute and the Broad Institute have found strikingly high levels of a bacterium in colorectal cancers, a sign that it might contribute to the disease and potentially be a key to diagnosing, preventing and treating it.


Hypertension may be misdiagnosed

20 October, 2011

70,000 Australians may have undetected high blood pressure because of sphygmomanometer errors, according to new study.


New way to screen for brain cancer discovered

18 October, 2011

Researchers have developed a new way to screen for brain cancer stem cell killers.


Researchers reconstruct genome of the 'Black Death'

18 October, 2011

An international research team based in Germany has sequenced the entire genome of the 'Black Death'.


Patent improves speed of DNA analysis

18 October, 2011

A US researcher has patented a process that reduces the time it takes to perform DNA analysis from hours to minutes.


Discovery of insulin switches in pancreas could lead to new diabetes drugs

30 September, 2011

Scientists have discovered how a hormone turns on a series of molecular switches inside the pancreas that increases production of insulin.


Thermo Fisher Scientific opens biomarker translational centre

08 September, 2011

Thermo Fisher Scientific has established a new biomarker translational centre in Cambridge Massachusetts. Their goal is to accelerate mass spectrometry-based biomarker discovery and its translation into the development of routine clinical assays for the clinical diagnostics market.


Cancers - parasites or newly evolved species?

05 September, 2011 by

Cancer patients may view their tumours as parasites taking over their bodies, but this is more than a metaphor for Peter Duesberg, a molecular and cell biology professor at the University of California, Berkeley.


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