A first-in-kind clinical trial has tested the safety and efficacy of a JAK inhibitor in decreasing the burden of autoimmune skin conditions in people with Down syndrome. [ + ]

In industrial processes and laboratories, vapours have a useful role. So what are vapours, where are they used, and how can they be delivered in a controlled way to these processes? [ + ]

The process of translating pain into a 'threat memory' occurs so quickly that scientists originally thought it must be mediated by fast-acting neurotransmitters, but it turns out this is not the case. [ + ]

An upright neuroimaging device allows patients to move around while undergoing a brain scan, addressing issues with traditional positron emission tomography scanners. [ + ]

Highly potent immune cells gather in regional bone marrow niches close to the glioblastoma tumour and organise the defence from there. [ + ]

This two-part series illuminates design and implementation principles for ensuring an efficient, reliable and cost-effective compressed air supply — which is often possible without major effort. [ + ]

Expectant mothers who eat a high-fibre diet can reduce the risk of heart disease in their offspring, while fathers' diets can program certain characteristics of the next generation even before conception. [ + ]

With elections this year in the US, the UK and India — all major players in the life sciences industry — what changes and benefits can we expect to see? [ + ]

Researchers have used a precise method of brain imaging to unveil how different parts of the brain work together in order to produce creative thought. [ + ]

US and Australian scientists have reported that more lung cell types can be infected by SARS-CoV-2 than previously thought, including those without known viral receptors. [ + ]

Researchers have developed a diagnostic platform that uses similar techniques to PCR, but within a handheld device rather than several benchtop machines. [ + ]

People who gain excess weight from their 20s onwards have less healthy hearts by their 60s, while those with healthy diets are more likely to be well-functioning at age 70. [ + ]

Angelman syndrome is a rare genetic disorder characterised by poor muscle control, limited speech, epilepsy and intellectual disabilities. [ + ]

Researchers have revealed that a wide range of PFAS (perfluoroalkyl substances) can permeate the skin barrier and reach the body's bloodstream. [ + ]

Scientists are potentially closer to an HIV immunisation regimen than ever before — one that could produce rare antibodies that would be effective against a wide range of HIV strains. [ + ]