Quality tissue cutting for Human Protein Atlas Project
22 March, 2012The Human Protein Atlas Project is using the Thermo Scientific HM355S automated microtome and Section Transfer System to create high-quality tissue sections during tissue microarray (TMA) production.
R & D Systems Proteome Profiler Antibody Arrays
07 February, 2012R & D Systems’ Proteome Profiler Antibody Arrays allow you to measure up to 119 proteins in a single sample.
BioTek Instruments ELx405 Select Deep Well Washer
08 August, 2011 byBioTek Instruments has launched the ELx405 Select Deep Well Washer, a robot-compatible, full plate washer for automated aspirate and dispense steps in 96- and 384-well plates up to 50 mm high. It can also accommodate standard 15 mm microplates and delivers increased washing efficiency compared to manual and handheld methods.
Millennium Science cAMP Alphascreen application note
25 May, 2011Adenosine 3′, 5′ cyclic monophosphate (cAMP) plays a critical role in the transmission of signals by functioning as a ‘second messenger’. Binding of hormones or ligands to their respective receptors can either inhibit or enhance the production of cAMP by changing the activity of the enzyme adenylate cyclase. Adenylate cyclase is a membrane-associated enzyme that catalyses the formation of cAMP from ATP. Intracellular cAMP levels, in turn, regulate enzymatic activity of numerous protein kinases, which phosphorylate specific targets setting off a cascade of cellular events. Because of the importance of cAMP as a cellular messenger, several different reading methodologies have been developed to measure cellular levels, one of which is AlphaScreen. Here we describe and demonstrate the ability of the Synergy 2 to quantitate cAMP using this methodology.
Lonza GeneSieve Bioanalysis software tool
18 April, 2011 byThe GeneSieve Bioanalysis software package enables users to find the most appropriate StellARray qPCR arrays or gene lists associated with a particular research area or gene
Wyatt Light Scattering DynaPro plate reader
08 February, 2011 byThe Wyatt Light Scattering DynaPro plate reader can perform accelerated stability, thermal melting and temperature studies on multiple samples in parallel.
Lonza 384 StellARray Alzheimer’s disease qPCR array
04 February, 2011 byThe 384 StellARray qPCR array is designed to profile the expression pattern of genes that may increase susceptibility, contribute towards the progression or provide a neuroprotective role in Alzheimer’s disease.
Millennium Science GloSensor cAMP assay
02 February, 2011 byG-protein coupled receptors (GPCRs) are an important protein family in pharmacological applications and drug discovery research as they are involved with many critical cellular signalling responses. Monitoring the response of GPCRs to a variety of agonist and antagonists is currently being investigated by academic researchers and drug discovery efforts. Traditionally, methods in cAMP quantification require cell lysis prior to detection of intracellular cAMP levels with a colorimetric readout. This method was improved by increasing sensitivity using methods such as TR-FRET and bead-based assays, though they were considered end-point assays and still required cell lysis prior to detection.
Millennium Science Take3 multivolume plates
02 February, 2011 byThe Take3 multivolume plates can be used to perform absorbance measurement over a wide range of applications and sample volumes in a BioTek microplate reader.
Harvard Apparatus 192-well DispoEquilibrium Dialyzers
07 October, 2010 byHarvard Apparatus ready-to-use, disposable 96-sample equilibrium dialysis plates are suitable for analysis of free or unbound analytes like free T4, free cortisol, free testosterone, or for protein-ligand binding studies.
BioTek Synergy H1 hybrid multimode microplate reader
07 October, 2010BioTek has released the Synergy H1 hybrid multimode microplate reader which expands the performance, versatility and flexibility offered by hybrid technology.
BioTek MultiFlo microplate dispenser
07 October, 2010BioTek’s MultiFlo microplate dispenser uses multiple technologies to dispense multiple reagents into multiple microplate types. This all-in-one dispenser saves bench space and transfer time and also eliminates plate set-up steps, thus simplifying the dispensing process.
SABiosciences RT2 Profiler PCR Arrays
04 August, 2010 bySABiosciences has released several RT2 Profiler PCR Arrays for gene expression profiling in nephrotoxicity, hepatotoxicology, differentiation and embryonic stem cells markers as well as analysis of epigenetic modulators and enzymes. Covering more than 100 pathways, PCR arrays enable scientists to easily and accurately analyse the gene expression in research areas such as cancer, stem cells, biomarker discovery and immunology.
Trek Sensititre MTB MIC Plate (Part MYCOTBI)
07 June, 2010 byThe Trek Sensititre MTB MIC Plate (Part MYCOTBI) is a dry MIC plate for M. tuberculosis isolates.
Agilent Technologies SurePrint G3 gene expression microarray
07 June, 2010 byAgilent Technologies has introduced the SurePrint G3 gene expression microarray, providing up to one million features per standard 1 x 3″ slide for added throughput, and coverage which includes both coding and non-coding RNA.
