Life science & clinical diagnostics instruments

BioTek cytokines ELx405 washer application note

25 May, 2011 | Supplied by: http://www.mscience.com.au/upload/pages/biotek/biorad_cytokine_app_note-2010.pdf

Cytokines and growth factors are cell signalling proteins that mediate a number of physiological responses. In addition, they are also associated with a number of diseases including tumour growth and metastasis, infections and inflammation. Because these molecules rarely act unilaterally it is important to assess a number of them in parallel. The advent of multiplex assays using Luminex xMAP bead technology has simplified the task of performing multiple assays on samples. BioTek has demonstrated how to automate the wash steps of the Bio-Rad HumanCytokine 8-plex assay kit using the ELx405 Magnetic Bead Washer.


BioTek HTRF AKT application note

25 May, 2011 | Supplied by: http://www.mscience.com.au/upload/pages/biotek/biotek-htrf-akt_app_note_automated-2011.pdf

AKT is a serine/threonine protein kinase that plays a key role in cellular processes. AKT has become a popular target for drug discovery campaigns, due to the fact that AKT inhibitors may help to treat a number of cancers. BioTek has demonstrated an automated homogeneous assay to probe AKT phosphorylation at its serine 473 residue using endogenous levels of kinase expression within human primary HUVEC cells.


Non-invasive ‘point of care’ haemoglobin monitoring coming closer

05 May, 2011

’Point of care’ monitoring of haemoglobin levels is nearing reality in operating rooms as a spectrophotometric haemoglobin sensor is providing a new approach to non-invasive monitoring of blood haemoglobin levels during surgery.


Do these genes make my backside look big?

05 May, 2011

An intriguing example of epigenetics is evident in the size of the backside of ‘callipyge’ sheep – leading to the genuine question: do these genes make my backside look big?


Life Technologies BigDye Direct Cycle Sequencing Kit

20 April, 2011 | Supplied by: Applied Biosystems Pty Ltd

Life Technologies has announced an advancement in capillary electrophoresis (CE) sequencing reagents that simplifies the Sanger sequencing workflow by combining post-PCR clean-up and cycle sequencing into a single step and allows reads as close as one base from the primer using POP-7 polymer.


Innova Biosciences imm-Link Immunogen Linking Kits

20 April, 2011 | Supplied by: BioNovus Life Sciences

Innova Biosciences imm-Link Immunogen Linking Kits simplify the conjugation of haptens to carrier proteins. Large immune responses are stimulated by BSA, ovalbumin and keyhole limpet hemocyanin (KLH) and are typically used as carrier proteins to generate antibodies against small antigens (eg, peptides or organic compounds - ie the ‘hapten’). To successfully stimulate the production of antibodies, the antigen needs to be covalently linked to a carrier protein.


Integrated DNA Technologies PrimeTime Pre-designed qPCR Assays

18 April, 2011 | Supplied by: Integrated DNA Technologies

PrimeTime Pre-designed qPCR Assays work for human, mouse and rat transcriptomes. Users can search and select from the online database that contains thousands of assays. All assays are designed to span exons, protect against non-specific amplifications, avoid known SNPs and minimise the impact of secondary structure. Consisting of two primers and a hydrolysis probe, all three components are shipped in a single tube and are claimed to provide \>90% efficiency.


Qiagen Investigator Quantiplex Kit

16 April, 2011 | Supplied by: QIAGEN Pty Ltd

The Investigator Quantiplex Kit has been designed to quickly confirm that forensic DNA samples contain sufficient DNA for genetic fingerprinting analysis. The kit quantifies the human DNA in the sample and establishes whether it contains inhibitors that may interfere with downstream applications.


Sigma Life Science and Cofactor Genomics rat genome database

15 April, 2011 | Supplied by: Merck

Sigma Life Science’s SAGE Labs initiative has partnered with Cofactor Genomics in an effort to sequence genomes for six of the most widely used strains of rat. As part of the agreement, Cofactor Genomics plans to generate and analyse sequence data using next-generation sequencing systems, while SAGE Labs plans to provide the samples and to host a new, free public database at sageresearchmodels.com in late 2011. The database will include exclusive genomic information and analysis tools.


Synbiosis ProtoCOL 2 automated colony counter

12 April, 2011 | Supplied by: Don Whitley Scientific Australia

The Synbiosis ProtoCOL 2 automated colony counter can be used to rapidly and accurately count colonies of yeast, used as a model system for human DNA repair research.


Enzo Life Sciences CGH labelling kit for oligo arrays

07 April, 2011 | Supplied by: United Bioresearch Products Pty Ltd

The Enzo Life Sciences CGH labelling kit for oligo arrays has been optimised to label DNA for dual sample comparative genomic hybridisation (CGH) assays on Agilent oligonucleotide arrays.


Coris BioConcept Legionella V-TesT for L. pneumophila antigen

16 March, 2011 | Supplied by: Dutec Diagnostics Pty Ltd

Coris BioConcept has introduced a Legionella V-TesT that detects soluble antigen from L. pneumophila serogroup 1 in urine and combines reasonable sensitivity, high specificity and rapid results. The ready-to-use membrane test is based on colloidal gold particles.


Location, location, location

02 March, 2011 by Sarah C P Williams

Biologists readily accept the general principle that location is intricately tied to function. Quantifying this is hard, however.


Biochrom Libra S80 UV-vis spectrophotometer

03 February, 2011 | Supplied by: Pacific Laboratory Products

Featuring a double-beam optical design and variable bandwidth (0.5, 1, 2 and 4 nm), Biochrom’s latest ‘top of the range’ UV-vis spectrophotometer is fully EP (European Pharmacopoeia) compliant. It is suitable for both research and method development laboratories. Users have the choice of local control via a colour touch screen or PC operation. A wide range of options including sample accessories, 21 CFR Part 11 compliant PC software and IQ/OQ documentation is available enabling the system to be customised for the user’s application.


Beckman Coulter MoFlo Astrios cell sorter

03 February, 2011 | Supplied by: Beckman Coulter Australia

The MoFlo Astrios next-generation cell sorter leverages the stable fluidic design of the original MoFlo and the electronic processing of the MoFlo XDP, while expanding sorting capabilities with an array of laser options. A range of software components further enhances instrument functionality.


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