Life science & clinical diagnostics instruments

Biotrin Intl to develop a nucleic acid test (NAT) analyser

17 June, 2011 | Supplied by: DiaSorin Australia Pty Ltd

DiaSorin has announced that its fully owned Irish subsidiary Biotrin International has signed an agreement with Precision System Science (PSS) of Japan for the development of a nucleic acid test (NAT) analyser.


Ion Torrent Ion OneTouch automated sample preparation system

16 June, 2011 | Supplied by: Applied Biosystems Pty Ltd

The Ion Torrent Ion OneTouch System is an automated sample preparation system for the Ion Personal Genome Machine (PGM) sequencer that eliminates complexity, reduces hands-on time to 5 min and offers walk-away convenience.


Single molecule sequencer

16 June, 2011

A gene expression technique adapted for single molecule sequencing has enabled researchers at the Riken Omics Science Center (OSC) to accurately and quantitatively measure gene expression levels using only 100 ng of total RNA. The technique, which pairs Riken’s Cap Analysis of Gene Expression (CAGE) protocol with the Helicos Genetic Analysis System opens the door to the detailed analysis of gene expression networks and rare cell populations.


Easy-to-use genome analyser offered

14 June, 2011

Scientists have developed a genome analyser and browser that allows biologists to analyse and process high-throughput data.


AES Chemunex Fluroassure flow cytometry technology

11 June, 2011 | Supplied by: In Vitro Technologies Pty Ltd

AES Chemunex Fluroassure flow cytometry technology can be used to detect bacteria, yeast and mould, enabling users to release products earlier. The system is suitable for early detection of viable microorganisms in juices, beverages, dairy products, process water, cosmetics and pharmaceuticals.


Norway harvests genomic expertise

10 June, 2011

Norway is cooperating with Canada and Chile to sequence the salmon genome. The knowledge generated could provide the answers to several problematic issues involving Norwegian farmed salmon - and lead to major competitive advantages for companies taking part in the project.


Sage-N Research signs microbial identification agreement

06 June, 2011

Sage-N Research has signed an exclusive agreement with the US Army Edgewood Chemical Biological Center (ECBC) to license technology for microbial identification.


The great cell race

01 June, 2011

Have you got the world’s fastest cell? Now, for the first time in history, you can race your cells in an international competition. If they win it will be by less than a hair’s breadth as the entire track length is only a hair’s breadth - 100 µm.


Gilson Trackman portable light box

31 May, 2011 | Supplied by: John Morris Scientific Pty Ltd

The Gilson Trackman portable light box can be used to keep track as users pipette from one microplate to another. The tool is claimed to simplify laboratory work, improve productivity and reduce pipetting errors and cross-contamination.


TTP LabTech Libra2 acoustic biosensor

31 May, 2011 | Supplied by: Millennium Science Pty Ltd

TTP LabTech’s acoustic biosensor, Libra2, can be used for the study of glycosylation patterns on cell membranes.


Epoch multi-volume nucleic acid quantification application note

25 May, 2011 | Supplied by: http://www.mscience.com.au/upload/pages/biotek/multi-volume_analysis_app_notefinal-2011.pdf

Nucleic acids isolated from a variety of sample types such as animal models, body fluids or eukaryotic and bacterial cells provide the starting material for a broad range of downstream applications including gene expression, genotyping, sequencing and cloning. Quantification of isolated nucleic acid is necessary prior to introduction into these applications. The Epoch Spectrophotometer System provides a means of obtaining accurate measurement over a wide range of sample concentrations and volumes, including microvolume quantification. Comparison to other microvolume dedicated devices, such as NanoDrop, shows equivalent performance.


BioTek HTRF AKT application note

25 May, 2011 | Supplied by: http://www.mscience.com.au/upload/pages/biotek/biotek-htrf-akt_app_note_automated-2011.pdf

AKT is a serine/threonine protein kinase that plays a key role in cellular processes. AKT has become a popular target for drug discovery campaigns, due to the fact that AKT inhibitors may help to treat a number of cancers. BioTek has demonstrated an automated homogeneous assay to probe AKT phosphorylation at its serine 473 residue using endogenous levels of kinase expression within human primary HUVEC cells.


Millennium Science cAMP Alphascreen application note

25 May, 2011 | Supplied by: http://www.mscience.com.au/upload/pages/biotek/camp_alphascreen_assay-2010.pdf

Adenosine 3, 5 cyclic monophosphate (cAMP) plays a critical role in the transmission of signals by functioning as a ‘second messenger’. Binding of hormones or ligands to their respective receptors can either inhibit or enhance the production of cAMP by changing the activity of the enzyme adenylate cyclase. Adenylate cyclase is a membrane-associated enzyme that catalyses the formation of cAMP from ATP. Intracellular cAMP levels, in turn, regulate enzymatic activity of numerous protein kinases, which phosphorylate specific targets setting off a cascade of cellular events. Because of the importance of cAMP as a cellular messenger, several different reading methodologies have been developed to measure cellular levels, one of which is AlphaScreen. Here we describe and demonstrate the ability of the Synergy 2 to quantitate cAMP using this methodology.


BioTek cytokines ELx405 washer application note

25 May, 2011 | Supplied by: http://www.mscience.com.au/upload/pages/biotek/biorad_cytokine_app_note-2010.pdf

Cytokines and growth factors are cell signalling proteins that mediate a number of physiological responses. In addition, they are also associated with a number of diseases including tumour growth and metastasis, infections and inflammation. Because these molecules rarely act unilaterally it is important to assess a number of them in parallel. The advent of multiplex assays using Luminex xMAP bead technology has simplified the task of performing multiple assays on samples. BioTek has demonstrated how to automate the wash steps of the Bio-Rad HumanCytokine 8-plex assay kit using the ELx405 Magnetic Bead Washer.


Non-invasive ‘point of care’ haemoglobin monitoring coming closer

05 May, 2011

’Point of care’ monitoring of haemoglobin levels is nearing reality in operating rooms as a spectrophotometric haemoglobin sensor is providing a new approach to non-invasive monitoring of blood haemoglobin levels during surgery.


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